Print OverviewEpididymitis (ep-ih-did-uh-MY-tis) is an inflammation of the coiled tube, called the epididymis, at the back of the testicle. The epididymis stores and carries sperm. Males of any age can get epididymitis. Epididymitis is most often caused by a bacterial infection, including sexually transmitted infections (STIs), such as gonorrhea or chlamydia. Sometimes, a testicle also becomes inflamed — a condition called epididymo-orchitis. Epididymitis is usually treated with antibiotics and measures to relieve discomfort.Products & ServicesA Book: Man Overboard!A Book: Mayo Clinic Family Health BookShow more products from Mayo Clinic Symptoms Epididymitis Enlarge image Close Epididymitis Epididymitis Epididymitis is an inflammation of the coiled tube, called the epididymis, at the back of the testicle. Symptoms of epididymitis might include: A swollen, discolored or warm scrotum Testicle pain and tenderness, usually on one side, that often comes on slowly Pain when you pass urine An urgent or frequent need to urinate Discharge from the penis Pain or discomfort in the lower abdomen or pelvic area Blood in the semen Less commonly, fever Chronic epididymitisEpididymitis that lasts longer than six weeks or that happens over and over again is considered chronic. Symptoms of chronic epididymitis might come on slowly. Sometimes the cause of chronic epididymitis isn't able to be found. When to see a doctorDon't ignore scrotal pain or swelling. This can be caused by a number of conditions. Some of them need treatment right away to avoid permanent damage. If you have severe pain in the scrotum, seek emergency treatment. If you have discharge from your penis or pain when you pass urine, see a health care provider. Request an appointment There is a problem with information submitted for this request. Review/update the information highlighted below and resubmit the form. From Mayo Clinic to your inbox Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview. Email Address 1 ErrorEmail field is required ErrorInclude a valid email address Learn more about Mayo Clinic’s use of data. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. Subscribe! Thank you for subscribing! You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry Causes Male reproductive system Enlarge image Close Male reproductive system Male reproductive system The male reproductive system makes, stores and moves sperm. The testicles produce sperm. Fluid from the seminal vesicles and prostate gland combines with sperm to make semen. The penis ejaculates semen during sexual intercourse. Causes of epididymitis include: STIs. Gonorrhea and chlamydia are the most common causes of epididymitis in young, sexually active males. Other infections. Bacteria from a urinary tract or prostate infection might spread from the infected site to the epididymis. Also, viral infections, such as the mumps virus, can result in epididymitis. Urine in the epididymis. This condition occurs when urine flows backward into the epididymis, causing chemical irritation. It may be the result of heavy lifting or straining. Trauma. A groin injury can cause epididymitis. Tuberculosis. Rarely, epididymitis can be caused by tuberculosis infection. Risk factorsCertain sexual behaviors that can lead to STIs put you at risk of sexually transmitted epididymitis, including having: Sex with a partner who has an STI Sex without a condom Anal sex A history of STIs Risk factors for epididymitis that's not sexually transmitted include: Having a prostate or urinary tract infection Having a medical procedure done that affects the urinary tract, such as insertion of a urinary catheter or scope into the penis An uncircumcised penis A difference in the typical anatomy of the urinary tract Prostate enlargement, which increases the risk of bladder infections and epididymitis Other health conditions that cause a weakened immune system, such as HIV ComplicationsComplications of epididymitis include: Pus-filled infection, called an abscess, in the scrotum Collection of fluid around the testicle, called a hydrocele Epididymo-orchitis, if the condition spreads from the epididymis to a testicle Rarely, reduced fertility PreventionTo help protect against STIs that can cause epididymitis, practice safer sex. If you have recurrent urinary tract infections or other risk factors for epididymitis, your health care provider might talk with you about other ways you can help prevent the condition. By Mayo Clinic Staff Request an appointment Diagnosis & treatment April 06, 2023 Print Show references Sexually transmitted infections treatment guidelines, 2021: Epididymitis. Centers for Disease Control and Prevention. https://www.cdc.gov/std/treatment-guidelines/epididymitis.htm. Accessed Sept. 7, 2022. Epididymitis. Merck Manual Professional Version. https://www.merckmanuals.com/professional/genitourinary-disorders/penile-and-scrotal-disorders/epididymitis#. Accessed Sept. 7, 2022. Khastgir J. Advances in the antibiotic management of epididymitis. Expert Opinion on Pharmacotherapy. 2022; doi:10.1080/14656566.2022.2062228. Ferri FF. Epididymitis. In: Ferri's Clinical Advisor 2023. Elsevier; 2023. https://www.clinicalkey.com. Accessed Sept. 7, 2022. Eyre RC. Acute scrotal pain in adults. https://www.uptodate.com/contents/search. Accessed Sept. 7, 2022. Eyre RC. Nonacute scrotal conditions in adults. https://www.uptodate.com/contents/search. Accessed Sept. 7, 2022. Lynch S. Acute epididymitis. Journal of the American Academy of Physician Assistants. 2018; doi:10.1097/01.JAA.0000530304.69021.4b Related Epididymitis Associated Procedures Ultrasound Urinalysis Products & Services A Book: Man Overboard! A Book: Mayo Clinic Family Health Book Show more products and services from Mayo Clinic EpididymitisSymptoms&causesDiagnosis&treatment Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship Policy Opportunities Ad Choices Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. 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There is a problem with information submitted for this request. Review/update the information highlighted below and resubmit the form. From Mayo Clinic to your inbox Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview. Email Address 1 ErrorEmail field is required ErrorInclude a valid email address Learn more about Mayo Clinic’s use of data. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. Subscribe! Thank you for subscribing! You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry